NSN 6515-01-537-4014

6515015374014

NO

08514

N/A

Multiple diagnostic testing

Lsi bcr/abl dual color, dual fusion translocation probe

Mixture of the lsi bcr probe labeled with spectrumgreen and the lsi abl probe labeled with spectrumgreen and the lsi abl probe labeled with sprectrumorange.The spanning abl probe has a genomic target of approx. 650 kb extending from an area centromic of the argininosuccinate synthetase gene (ass) to well telomeric of the last abl exon.The bcr probe target spans a genomic distance of about 1.5 mb.The bcr probe begins with the variable segments of the immunglobulin lamdba light chain locu (iglv) , extends along chromosome 22 through the bcr gene, and ends at the point approx. 900 kn telomeric of the bcr. A region of about 300 kb containing low copy number repeats has been elimated from the probe which introduces a gap in the coverage of the probe target.Both probes span their respective breakpoints